e000fe09 - The directory is invalid

We're having issues backing up the boot (C:\) and data (D:\) partitions on one of our Oracle DB servers (Windows - non RAC).  I can backup the Oracle database and the system state via Backup Exec just fine.  The job is failing when it attempts to process the individual volumes. 

I've tried creating a separate backup job and selected a subset of individual files on the boot partition but the job still fails.

The job log simply states:

Resource Name:  \\ServerName\C:
Error:  e000fe09 - The directory is invalid.

I've opened a support ticket with Symantec on the issue, but it's been languishing for about 2 weeks.  I'm hoping someone from the forums has come across this issue and can recommend a viable solution.